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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAPK15 All Species: 18.79
Human Site: T175 Identified Species: 41.33
UniProt: Q8TD08 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TD08 NP_620590.2 544 59832 T175 G P E D Q A V T E Y V A T R W
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539201 559 60934 T176 E P A G Q A L T D Y V A T R W
Cat Felis silvestris
Mouse Mus musculus Q80Y86 549 60660 T176 G P G G Q A L T E Y V A T R W
Rat Rattus norvegicus Q9Z2A6 547 60705 T176 G P G G Q A L T E Y V A T R W
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423954 600 66936 T200 E Q S S P A L T E Y V A T R W
Frog Xenopus laevis P26696 361 41238 A32 G P R Y I N L A Y I G E G A Y
Zebra Danio Brachydanio rerio NP_001018581 524 58806 T176 D A G N P A L T E Y V A T R W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392445 747 85295 D183 G D G E T A S D P T L T D Y V
Nematode Worm Caenorhab. elegans Q11179 470 54020 S141 L H R D L K P S N V L L D A D
Sea Urchin Strong. purpuratus XP_001203135 583 64666 A175 V L S E D N P A L T E Y V A T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P14681 368 42674 V39 H K P S G I K V A I K K I Q P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 71.5 N.A. 69.2 68.7 N.A. N.A. 45.3 28.6 48.3 N.A. N.A. 34.6 42.6 44.9
Protein Similarity: 100 N.A. N.A. 77.8 N.A. 75.5 75.1 N.A. N.A. 60 42 64.8 N.A. N.A. 50.5 61.2 62.6
P-Site Identity: 100 N.A. N.A. 66.6 N.A. 80 80 N.A. N.A. 60 13.3 60 N.A. N.A. 13.3 6.6 0
P-Site Similarity: 100 N.A. N.A. 80 N.A. 86.6 86.6 N.A. N.A. 66.6 26.6 73.3 N.A. N.A. 26.6 20 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 29.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 0 0 64 0 19 10 0 0 55 0 28 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 10 0 19 10 0 0 10 10 0 0 0 19 0 10 % D
% Glu: 19 0 10 19 0 0 0 0 46 0 10 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 46 0 37 28 10 0 0 0 0 0 10 0 10 0 0 % G
% His: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 10 0 0 0 19 0 0 10 0 0 % I
% Lys: 0 10 0 0 0 10 10 0 0 0 10 10 0 0 0 % K
% Leu: 10 10 0 0 10 0 55 0 10 0 19 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 19 0 0 10 0 0 0 0 0 0 % N
% Pro: 0 46 10 0 19 0 19 0 10 0 0 0 0 0 10 % P
% Gln: 0 10 0 0 37 0 0 0 0 0 0 0 0 10 0 % Q
% Arg: 0 0 19 0 0 0 0 0 0 0 0 0 0 55 0 % R
% Ser: 0 0 19 19 0 0 10 10 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 10 0 0 55 0 19 0 10 55 0 10 % T
% Val: 10 0 0 0 0 0 10 10 0 10 55 0 10 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 55 % W
% Tyr: 0 0 0 10 0 0 0 0 10 55 0 10 0 10 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _